产品编号
1019490
CAS 号
130-85-8
中文名称
帕莫酸
MDL 号
MFCD00004079
分子量
388.38
存储条件
2-8°C, protect from light, stored under nitrogen
网页展示纯度为入库指导纯度值，各批次间存在一定差异，实际纯度以收货为准
熔点
315 °C
沸点
434.1 °C at 760 mmHg
闪点
旋光
描述
TPSA
115.06
LogP
4.3914
H_Acceptors
4
H_Donors
4
Rotatable_Bonds
4
[1]. Ozayra Sharmin, et al. Activation of GPR35 protects against cerebral ischemia by recruiting monocyte-derived macrophages. Sci Rep. 2020 Jun 10;10(1):9400.
[2]. Pingwei Zhao, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Mol Pharmacol. 2010 Oct;78(4):560-8.
[3]. Corinne Hazan, et al. Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. BMC Struct Biol. 2008 Apr 16:8:22.
[4]. H M Ruijten, et al. Conical precolumn as loading buffer for the main column. J Chromatogr. 1984 Nov 30:314:183-91.
[5]. Hong-Yu Hu, et al. Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. J Biol Chem. 2004 Sep 17;279(38):39736-44.
警示图
警示词
Warning
危险申明
H302-H315-H319-H335
警告申明
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P321-P330-P337-P362+P364-P403+P233-P405-P501
GHS 编码
GHS07
1249843 现货
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