产品编号
1039561
CAS 号
6736-58-9
中文名称
3-脱氮腺苷
MDL 号
MFCD00153951
分子量
266.25
存储条件
-20°C
网页展示纯度为入库指导纯度值,各批次间存在一定差异,实际纯度以收货为准
熔点
228-229°C
沸点
闪点
旋光
描述
TPSA
126.65
LogP
-1.375
H_Acceptors
8
H_Donors
4
Rotatable_Bonds
2
[1]. Gordon RK, et al. Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners. Eur J Biochem. 2003 Sep;270(17):3507-17.
[2]. Jeong SY, et al. 3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation. J Biol Chem. 1999 Jul 2;274(27):18981-8.
[3]. Sedding DG, et al. 3-Deazaadenosine prevents smooth muscle cell proliferation and neointima formation by interfering with Ras signaling. Circ Res. 2009 May 22;104(10):1192-200.
[4]. Alexander C Langheinrich, et al. 3-Deazaadenosine inhibits vasa vasorum neovascularization in aortas of ApoE(-/-)/LDL(-/-) double knockout mice. Atherosclerosis. 2009 Jan;202(1):103-10.
[5]. Cynthia J DeLong, et al. Disruption of choline methyl group donation for phosphatidylethanolamine methylation in hepatocarcinoma cells. J Biol Chem. 2002 May 10;277(19):17217-25.
警示图
警示词
Danger
危险申明
H302+H312-H315-H319-H331-H335
警告申明
P264-P270-P321-P330-P405-P501
GHS 编码
GHS06
危险类别
6.1
UN 编码
2811
包装等级
Ⅱ
现货供应
专业护航
售后无忧
品质保障
无需凑单