Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Des(dimethylamino)-Afatinib is an impurity of Afatinib ( ). Afatinib is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
参考文献
Nakao, K., et al.: Sci. Rep., 9, 18202 (2019); Ebert, K, PLoS One, 14, 0223225 (2019)
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