3-AMINOPYRROLIDIN-2-ONE HCL (cas# 117879-49-9) is the hydrochloride salt of 3-Aminopyrrolidin-2-one (cA629968) which is used in the preparation of conformationally restricted inhibitors of angiotensin-converting enzyme. It is also used in the preparation of 2-aminoquinolines as melanin concentrating hormone receptor (MCH-1R) antagonists. Additionally, it is used in the preparation of cycloalkyl, lactam, lactone, and related compounds for inhibiting β-amyloid peptide release and/or its synthesis.
参考文献
Thorsett, E., et al.: J. Med. Chem., 29, 251 (1986); Devita, R., et al.: PCT Int. Appl. (2003), WO 2003045313 A2; Wu, J., et al.: PCT Int. Appl. (1998), WO 9828268 A2
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