β-Amino-γ,γ-difluoro-benzenepropanol is synthesized from cinnamyl alcohol (C442110). Cinnamyl alcohol is used as a fragrance ingredient and is a known a cause of allergic dermatitis in humans. Cinnamyl alcohol is also part of a group of cinnamic acid derivatives (for example: 4-Methoxycinnamic acid -M262150) that might be useful for the treatment of diabetes and obesity.
参考文献
Adisakwattana, S., et al.: J. Emzym. Inhib., 28, 1067, (2013); Basketter, D.: Acta-Derm.-Venereol., 72, 264 (1992); Letizia, C. S., et al.: Food Chem. Toxicol., 43, 837 (2005);
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