2-Amino-4-methylimidazole is used as a reagent in the synthesis of 1H-pyrrolo[2,3-c]pyridine-7-carboxamides as novel allosteric mGluR5 antagonists. Also used as a reagent in the synthesis of imidazo[1,2-a]pyrimidin-5(1H)-ones as beta isoform selective phosphatidylinositol 3-kinase (PI3K) inhibitors.
参考文献
Koller, M., et al.: Bioorg. Med. Chem. Lett., 22, 6454 (2012); Lin, H., et al.: Bioorg. Med. Chem. Lett., 22, 2230 (2012)
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