(R)-3-Amino-2-methylpropanoic Acid blood concentration increases in human body with exercise and may contribute to exercise-induced protection from metabolic diseases. It is a product of catabolism of thymine and is therefore present in low concentration in urine of patients with a deficiency of dihydropyrimidine dehydrogenase (DPD) which is vital in first step of pyrimidine degradation.
参考文献
Van Kuilenburg, A., et al.: Biochem. J., 379, 119 (2004); Roberts, L., et al.: Cell Metab., 19, 96 (2014);
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