2-(Azetidin-1-yl)ethanol is used to prepare novel proline and morpholine derivatives as inhibitors of 11-β-hydroxysteroid dehydrogenase type 1 (11-β-hsd-1) for treatment of diabetes and obesity. It is also used in the synthesis of antitumor dibenzonaphthyridine derivatives.
参考文献
Cheng, H., et al.: PCT Int. Appl. (2005), WO 2005108359 A1 20051117; Gopalsamy, A., et al.: U.S. Pat. Appl. Publ. (2007), US 20070135429 A1 20070614.