Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
1-Benzyl-4-methyl-3-piperidinamine is an intermediate of Tofacitinib (T528000); an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
参考文献
Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)
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