Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
N,N'-Bis(4-pyridyl)urea is an impurity of Dalfampridine (D113500) which is used to improve walking in people suffering from multiple sclerosis. N,N'-Bis(4-pyridyl)urea may be used for treating injured mammalian nerve tissue.
参考文献
Judge S., et al.: Pharmacol. Ther., 111, 224 (2006), Wu, Z.Z., et al.: J. Biol. Chem., 284. 36453 (2009); Borgens, R., et al.: Pyridines for treating injured mammalian nerve tissue, US Patent 20110130429, Jun 2, 2011;
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