Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Bufexamac is a non-steroidal anti-inflammatory drug used topically as well as rectally. Formulations containing Bufexamac is used by many patients with eczematous disorders as an alternative to topical corticosteroids.
参考文献
Bantscheff, M. et al.: Nature Biotechnol., 29, 255 (2011); Kranke, B. et al.: Cont. Derm., 36, 212 (1997);
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