N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester is an impurity in the synthesis of Gyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.
参考文献
Mizukami, et al.: Arzneimittel-Forsch., 19, 1413 (1969); Efendic, S., et al.: Proc. Nat. Acad. Sci. USA, 76, 5901 (1979); Feldman, J.M.: Pharmacotherapry, 5, 43 (1985);
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