8-chloro-3-methoxy-1,5-naphthyridine can be used in the preparation of cyclopropane dicarboxamides for treating kinase-dependent disorders. It can be used in the preparation of N-substituted benzamides as Aurora kinase modulators useful in cancer-related diseases. It is also useful in the preparation of C5-C6-carbocyclic fused iminothiadiazine dioxides as BACE inhibitors for treatment of Alzheimer's disease and related disorders.
参考文献
Bannen, L. C., et. al.: PCT Int. Appl., 236pp. (2019); Deak, H. L., et. al.: U.S. (2015); Scott, J. D., et. al.: PCT Int. Appl., 105pp. (2017)
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