4-Cyanobenzaldehyde is used as a reagent in the synthesis of hydrazone based inhibitors of adipose-triglyceride lipase (ATGL). 4-Cyanobenzaldehyde is also used as a reagent in the synthesis of BAZ2-ICR which is a chemical probe targeting the bromo domains of BAZ2A and BAZ2B.
参考文献
Mayer, N., et al.: Bioorg. Med. Chem., no vol., no pp (2015, ahead of print); Drouin, L., et al.: J. Med. Chem., 58, 2553 (2015)