Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level.
参考文献
Yin, L., et al.: PLoS One., 7, 48048 (2012); Rodriguez, J.D.,e t al.: Chem. Biochem. Engin. Quart., 20, 173 (2006);