Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
N-Desmethyl (E)-Doxepin Hydrochloride is an impurity of Doxepin Hydrochloride (D550000) used clinically to treat anxiety and depression. Doxepin is an antidepressant.
参考文献
Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965), Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969), Pinder, R.M., et al.: Drugs, 13, 161 (1977), Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985),
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