Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
(E)-N-(2-(6,7-Dihydro-1H-indeno[5,4-b]furan-8(2H)-ylidene)ethyl)propionamide is a key intermediate in the preparation of ramelteon (R110051). Ramelteon is a Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.
参考文献
Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),
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