Building Blocks; Research Tools; Miscellaneous; Molecular Biology; Enzyme Activators and Inhibitors;
应用
3-[[2-(Dimethylamino)ethyl]oxy]aniline Dihydrochloride is used in the preparation of thiazole and oxazole kinase inhibitors for cancer treatment. It is also used in the preparation of imidazopyridines as inhibitors of IGF-1R and IR and one or both of EGFR and ErbB2 kinases for treating neoplasm.
参考文献
Adjabeng, G., et. al.: PCT Int. Appl., 301 pp. (2009); Kuntz, K., et. al.: U.S. Pat. Appl. Publ., 249 pp. (2008)
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