Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用
Diallyl Tetrasulfide is a mitotic inhibitor and apoptosis inducers. An anti-carcinogenic agent. Also, it is derived from Allyl Bromide (A549655), which is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constitutent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.
参考文献
Yagdi Efe, E., et al.: Cancer Lett., 410, 139-157 (2017); Saidu, N. E. B., et al.: Biochim. Biophys. Acta, 1830, 5267-5276 (2013); Powell, R.G., et al.: Phytochemistry, 35, 335 (1994), Jeandet, P., et al.: J. Phytopathol., 143, 135 (1995), Mattivi, F., et al.: J. Agric. Food Chem., 43, 1820 (1995); Mulakayala, C. et al.: J. Mol. Graph. Model., 41, 43 (2013);
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