Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用
6,7-Dichloro-1,2,3,4-tetrahydro-isoquinoline Hydrochloride is derived from Glycinal Dimethyl Acetal (G616495), which is a versatile building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of a series of novel pyrazolo[1,5-a]pyrazine derivatives. Also, it is a Phenylethanolamine N-Methyltransferase and epinephrine biosynthesis inhibitor.
参考文献
Zaremba, O. V., et al.: Chem. Heterocyclic Comp., 49, 915 (2013); Bondinell, W. E., et al.: J. Med. Chem., 23, 506-511 (1980)
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