7-(Difluoromethyl)-1,2,3,4-tetrahydroquinoline, is a building block used in the synthesis of GNE-781 (D447825), a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP).
参考文献
Romero, F.A.; et al.: J. Med. Chem, DOI: 10.1021/acs.jmedchem.7b00796 (2017)
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