Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
2-(3,4-Dimethoxybenzoyl)pyridine was synthesised and evaluated as potentially showing more antiinflammatory activity against carrageenan-induced edema in rat paws than 2-benzoylpyridine (B209570) in an effort to increase the efficacy of the latter. It was used as a reagent in the synthesis of 3,4-dihydroxyphenyl-(2-piperidyl)carbinols which are cyclic adrenaline derivatives, the most active of which may be potential powerful bronchodilators.
参考文献
Hardtmann, G., et al.: J. Med. Chem., 12, 1093 (1969); Sankey, G., et al.: J. Heterocylic Chem., 9, 1049 (1972);
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