Diphenylphosphinic Acid acts as a reagent in the preparation of the HIV-Attachment Inhibitor BMS-663068 via Friedel-Crafts acylation/hydrolysis and amidation. Diphenylphosphinic Acid is used as an active ingredient in the preparation of highly efficient flame-retardant melanine salt (DPPMA). It also functions as a reagent for the asymmetric pilot-scale synthesis of TV-45070, a chiral spiro-ether that has a potential for topical pain therapy.
参考文献
Zheng, B., et al.: Org. Process Res. Dev., 21, 1145 (2017); Sclafani, J. A., et al.: Org. Process Res., Dev. PagesAhead of Print (2017); Rao, W., et al.: Ind. Eng. Chem. Res., 56, 7112 (2017)
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