Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
2-(1-Ethylpropyl)-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one is an intermediate in the synthesis of Deshydroxy Posaconazole Impurity (A6480252), which is a 2,2,5-tetrahydrofuran regioisomers of SCH 51048 (A648025) that exhibit antifungal activity.
参考文献
Lovey, R.G.; et al.: Bioorganic Med. Chem. Lett, 12, 1739 (2002)
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