英文名称
3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)
纯度
98%
网页展示纯度为入库指导纯度值，各批次间存在一定差异，实际纯度以收货为准
White to Pale Yellow Solid
DMSO (Slightly), Methanol (Slightly)
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogenesis through inhibiting JNK and p38 MAPK pathways in AMD, glaucoma, DR, and RVO animal models.
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