Ethyl 8-chloro-6-hydroxyoctanoate is used in biological study for the enzymic resolution of chiral chlorohydrin precursor for (R)-α-lipoic acid synthesis via lipase catalyzed enantioselective transacylation with vinyl acetate.
参考文献
Zhou, W. et al.: Journal of Molecular Catalysis B: Enzymatic (2014), 99, 102-107
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