Ethyl Dichlorophosphate is an intermediate used in the synthesis of b-D-2'-deoxy-2'-a-fluoro-2'-b-C-methyluridine nucleotide prodrug (PSI-7977) for treatment of hepatitis C virus. It is also used to prepare dialkylphosphocholines with antiprotozoal, antifungal and antitumor activities.
参考文献
Sofia, M., et al.: J. Med. Chem., 53, 7202 (2010); Lukac, M., et al.; Bioorg. Med. Chem. Lett., 19,6346 (2009)
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