8-Fluorooctanoic acid is used in the synthesis of a monofluoro 3-alkyl-2-hydroxy-1,4-naphthoquinone as a potential anti-malarial drug. It is also used in site-specific fluorination of biomolecules catalyzed by lipoic acid ligase.
参考文献
Kim, E., et al.: Tetrahedron Lett., 56, 6707 (2015); Drake, C., et al.: ACS Chem. Biol., 11, 1587 (2016)