Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine (Paroxetine EP Impurity G) is a 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs which inhibit the oxidation of benyzlamine by bovine plasma amine oxidase. Suitable as substrates for monoamine oxidase B and possesses dopaminergic neurotoxicity.
参考文献
Bhatti, A. R., et al.: J. Neurochem., 50, 1097-1104 (1988); Riachi, N. J., et al.: J. Neurochem., 50, 1319-1321 (1988)
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