Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
4-(Hydroxymethyl)benzoic Acid (Eprosartan USP Related Compound E) is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.
参考文献
Katane, M., et al.: J. Med. Chem., 56, 1894 (2013); Siddiqui, B.S., et al.: J. Ethnopharmacol., 144, 220 (2012);
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