(S)-3-Hydroxymethylmorpholine is a chemical reagent used in the synthesis of Aurora kinase inhibitors, used for their anti-tumor activity. Also used in the preparation of human epidermal growth factor receptor 1 & 2 kinase inhbitors in the treatment of solid tumors.
参考文献
Belanger, D. et al.: Bioorg, med. Chem. Lett., 20, 6739 (2010); Gavai, A. et al.: J. Med. Chem., 52, 6527 (2009);
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