Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用
N-[(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]carbamic acid 1,1-dimethylethyl ester is an impurity of Darunavir (D193500), a human immunodeficiency virus (HIV) protease inhibitor that is used to treat patients with drug-resistant HIV.
参考文献
Babu, K., et al.: Pharm. Chem., 3, 389 (2011); Back, D., et al.: Antivir. Ther., 13, 1 (2007); Ghosh, A., et al.: Bioorg. Med. Chem., 15, 7576 (2007)
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