Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用
8-[(6-Iodo-1,3-benzodioxol-5-yl)thio]-9H-purin-6-amine is used in the development of mitochondrial TRAP1 inhibitor that suppresses cell death and reprograms energy metabolism in cancer cells.
参考文献
Lee, C., et al.: J. Am. Chem. Soc., 137, 4358 (2015); Taldone, T., et al.: J. Med. Chem., 56, 6803 (2013)
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