Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
(S)-(E,Z)-1-(4-Chlorobenzylideneamino)-3-chloropropan-2-ol is an impurity of Linezolid(L466500). Linezolid is a prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.
参考文献
Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996), Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996), Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998), Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002),
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