Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
1-(2-Methyl-1H-benzo[d]imidazol-1-yl)ethanone is an impurity of Filbanserin (F336750), an agonist of serotonin-5HT1A receptor and an antagonist of the 5-HT2A receptor. Binds dopamine receptors with Ki values ranging from 4-24 nM. Used to treat hypoactive sexual desire disorder in females.
参考文献
Robinson, K. et al.: Annals. Pharmacother., 50, 125 (2016); Baksh, S. et al.: Drug Safe., 39, 375 (2016);
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