Methyl (R)-5-(2-bromo-1-hydroxyethyl)-2-(phenylmethoxy)benzoate is used in the preparation of phenylpyrazinoylguanidines as sodium channel blockers possessing β-agonist activity. These compounds are useful for promoting hydration of mucosal surfaces and treating a variety of disease conditions.
参考文献
Johnson, M.R.; et al.: U.S. No pp. given Patent 2012 CODEN:USXXAM
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