Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
(R)-(-)-2-Methylglycidyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
参考文献
Sasaki, H., et al.: J. Med. Chem., 49, 7854 (2006);
沪ICP备17019645号
400-821-0725
