Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用
4-[2-(Methyl-2-pyridinylamino)ethoxy]benzaldehyde is used in the preparation, molecular docking and SAR of imino-(methyl(pyridyl)aminoethoxy)benzylidene-thiazolidinones as protein tyrosine phosphatase 1B inhibitors and evaluation of their antitumor activity. 4-[2-(Methyl-2-pyridinylamino)ethoxy]benzaldehyde is also used in the synthetic optimization of rosiglitazone and related intermediates for industrial purposes.
参考文献
Meng, G., et al.: Eur. J. Med. Chem., 122, 756-769 (2016); Meng, G., et al.: Res. Chem. Intermediat., 42, 2023-2033 (2016)
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