N-Methyltrifluoroacetamide is a useful synthetic intermediate. It is used to prepare electrophilic 11b-aryl derivs. of estradiol as steroidal affinity labels of the estrogen receptor a. It is also used to synthesize amino substituted derivatives of 5'-amino-5'-deoxy-5'-noraristeromycin as antiviral agent.
参考文献
Aliau, S., et al.: J. Med. Chem., 43, 613 (2000); Yang, M., et al.: Bioorg. Med. Chem., 13, 877 (2005)
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