Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用
(3R)-N-[(1S)-1-Phenylethyl]-1-azabicyclo[2.2.2]octan-3-amine Dihydrochloride is the derivative of 3-Quinuclidinone Hydrochloride (Q795795), which is used in the synthesis of cevimeline, a thiolating agent. Also used in the preparation of novel CB1 and CB2 cannabinoid receptor ligands.
参考文献
Pramanik, C. et al.: Tetrahedron Lett., 54, 3043 (2013); Madadi, N. et al.: Bioorg. Med. Chem. Lett., 23, 2019 (2013)
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