Building Blocks; Miscellaneous; Molecular Biology;
应用
4-(2-(Pyrrolidin-1-yl)ethyl)aniline Hydrochloride is a salt analog of 4-[2-(1-Pyrrolidinyl)ethyl]aniline (CAT# B292253). 4-[2-(1-Pyrrolidinyl)ethyl]aniline can be useful in the preparation of ebselen derivatives as glutathione peroxidase mimics and cholinesterase inhibitors, preparation of 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents, preparation of pyridopyrimidinones as antiinflammatory macrophage colony-stimulating factor-1 receptor inhibitors, and synthesis of 2-amino-4-aryl-5-chloropyrimidine analogues and 4-aryl-5-cyano-2-aminopyrimidines as inhibitors of VEGFR-2. It can also be useful in the characterization of small-molecule scaffolds that bind to Shigella type III secretion system protein IpaD, and discovery of a novel series of
参考文献
Luo, Z., et al.: Bioorg. Med. Chem., 22, 1355 (2014); Wang, L., et al.: Eur. J. Med. Chem., 46, 285 (2010); Huang, H., et al.: J. Med. Chem., 52, 1081 (2009); Huang, S., et al.: Bioorg. Med. Chem. Lett., 17, 2179 (2007); Hughes, T. V., et al.: Bioorg. Med. Chem. Lett., 17, 3266 (2007); Dey, S, et al.: ChemMedChem, 12, 1534 (2017); Caldwell, R., et al.: Bioorg. Med. Chem. Lett., 28, 3419 (2018)
沪ICP备17019645号
400-821-0725
