1,2,3,4-Tetrahydropyrido[3,4-b]pyrazine is used in a study of aminopyridines and their pharmacokinetics, side effects, and antidote effect on botulinum neurotoxin intoxication. It is also used in a continuous flow strategy for preparation and elaboration of semi-saturated heterobicyclic fragments for fragment-based drug discovery (FBDD) programs.
参考文献
Mayorov, A. V., et al.: ACS Chem. Biol., 5, 1183 (2010); Luise, N., et al.: Eur. J. Org. Chem., 2019, 1341 (2019)
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