(9R)-6,7,8,9-Tetrahydro-9-hydroxy-5H-cyclohepta[b]pyridin-5-one is used in the synthetic preparation of CGRP antagonist BMS-846372 via chemoselective and enantioselective reduction of cyclohepta[b]pyridine-5,9-dione.
参考文献
Leahy, D.K., et al.: Org. Lett., 14, 4938 (2012); Bell, I., et al.: Bioorg. Med. Chem. Lett., 16, 6165 (2006)
沪ICP备17019645号
400-821-0725
