Tetrahydro-2H-pyran-3-methanamine Hydrochloride is a reagent in the synthesis of isoxazolo-pyridine derivatives which have affinity and selectivity for the GABA A α5 receptor binding site. The isoxazolo-pyridine derivatives are also used as cognitive enhancers or for the treatment of cognitive disorders like Alzheimer’s disease.
参考文献
Buettelmann, B., et al.: Preparation of isoxazolo-pyridine derivatives as modulaters of GABA A α5 receptor. U.S. Pat. Appl. Publ. US 20090143371 A1 20090604. Jun 4, 2009
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