Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用
3-(2-Thienyl)acrylic Acid is used as a phenylalanine derivative which shows improved intestinal absorption of insulin in mice. In addition it has been used in the synthesis of novel benzothiazepinones as glycogen synthase kinase-3b inhibitors.
参考文献
Amino, Y. et al.: Chem. Pharm. Bull., 36, 4426 (1988); Zhang, P. et al.: Bioorg. Med. Chem. Lett., 22, 7232 (2012);
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