Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Controlled Substances and Drugs of Abuse for Forensic Testing; Tryptamines;
应用
5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indole-3-ethanol is an intermediate in the synthesis of Rizatriptan Benzoate (R545000); a selective serotonin 5-HT1D receptor agonist and a potential anti-migraine drug.
参考文献
Cheng, H., et al.: Biopharm. Drug Dispos., 17, 17 (1996); Visser, W.H., et al.: rch. Neurol., 53, 1132 (1996); Chem, Ch., et al.: Tetrahedron Lett., 35, 6981 (1994)
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