4-Trifluoromethylpyridin-2-ol is used in the synthesis of sphingosine phosphate receptor selective allosteric agonists. The sphingosine phosphate receptor remains important in a multitude of biological processes including tumor cell survival and fibroblast chemotaxis.
参考文献
Satsu, H. et al.: Bioorg. Med. Chem., 21, 5373 (2013);
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